I really apologize for the major software architecture change from Apple… Maybe if enough people with the same problem complain, Wacom will do something, though given their pattern, I am not optimistic. Here's the Twitter thread: Wacom on Twitter: 'Hi, thanks for reaching out. When I asked for details, I got this reply, 'We totally understand your concern, but related to operating system upgrades, it is imperative to make sure all the hardware connected to a computer will be compatible with the newer operating system version before performing the upgrade.°VR.'

Our Bamboo tablets will still work with prior versions like 10.11. I really apologize for the major software architecture change from Apple's macOS, which has turned our Bamboo tablets incompatible due to technological advancements. I wrote to Wacom via their Twitter account, and they said, 'Hi, thanks for reaching out.

If you are looking at the Accessibility section and don't see all of the items, it is likely because the driver you installed does not install them.